Description
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Description
Hydrocodone is a semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.
How should this medicine be used?
Hydrocodone comes as an extended-release (long-acting) capsule and an extended-release (long-acting) tablet to take by mouth. The extended-release capsule is usually taken once every 12 hours. The extended-release tablet is usually taken once daily. Take hydrocodone at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydrocodone exactly as directed by your doctor.
How should this medicine be used?
Hydrocodone comes as an extended-release (long-acting) capsule and an extended-release (long-acting) tablet to take by mouth. The extended-release capsule is usually taken once every 12 hours. The extended-release tablet is usually taken once daily. Take hydrocodone at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydrocodone exactly as directed by your doctor.
Swallow the extended-release capsules or extended-release tablets one at a time with plenty of water. Swallow each capsule or tablet as soon as you put it in your mouth. Do not presoak, wet, or lick the extended-release tablets before you put them in your mouth.
Your doctor will probably start you on a low dose of hydrocodone and may gradually increase your dose, not more than once every 3 to 7 days if needed to control your pain. After your take hydrocodone for a period of time, your body may become used to the medication. If this happens, your doctor may increase your dose of hydrocodone or may prescribe a different medication to help control your pain. Talk to your doctor about how you are feeling during your treatment with hydrocodone.
Do not stop taking hydrocodone without talking to your doctor. If you suddenly stop taking hydrocodone, you may experience withdrawal symptoms such as restlessness, teary eyes, runny nose, yawning, sweating, chills, hair standing on end, muscle pain, widened pupils (black circles in the middle of the eyes), irritability, anxiety, back or joint pain, weakness, stomach cramps, difficulty falling asleep or staying asleep, nausea, loss of appetite, vomiting, diarrhea, fast breathing, or fast heartbeat. Your doctor will probably decrease your dose gradually.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking hydrocodone, tell your doctor and pharmacist if you are allergic to hydrocodone, any other medications, or any of the ingredients in hydrocodone extended-release capsules or extended-release tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the
IMPORTANT WARNING section and any of the following medications: antihistamines (found in cough and cold medications); amiodarone (Nexterone, Pacerone); azithromycin (Zithromax, Zmax); butorphanol; chlorpromazine; citalopram (Celexa); cyclobenzaprine (Amrix); dextromethorphan (found in many cough medications; in Nuedexta); dronedarone (Multaq); haloperidol (Haldol); laxatives such as lactulose (Cholac, Constulose, Enulose, others); levofloxacin (Levaquin); lithium (Lithobid); medications for irritable bowel disease, Parkinson’s disease, ulcers, and urinary problems; medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), and zolmitriptan (Zomig); mirtazapine (Remeron); nalbuphine; pentazocine (Talwin); 5HT3 serotonin blockers such as alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran, Zuplenz), or palonosetron (Aloxi); selective serotonin-reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), and sertraline (Zoloft); serotonin and norepinephrine reuptake inhibitors such as desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), milnacipran (Savella), and venlafaxine (Effexor); trazodone (Oleptro); or tricyclic antidepressants (‘mood elevators’) such as amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil). Also tell your doctor or pharmacist if you are taking or receiving the following medications or have stopped taking them within the past two weeks: isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). Many other medications may also interact with hydrocodone, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
Tell your doctor what herbal products you are taking, especially St. John’s wort and tryptophan.
tell your doctor if you have any of the conditions mentioned in the IMPORTANT WARNING section, a blockage or narrowing of your stomach or intestines, or paralytic ileus (condition in which digested food does not move through the intestines). Your doctor may tell you not to take hydrocodone.
tell your doctor if you have or have ever had low blood pressure, difficulty urinating, seizures, or thyroid, gall bladder, pancreas, liver, or kidney disease. If you are taking the extended-release tablets, also tell your doctor if you have or have ever had difficulty swallowing, colon cancer (cancer that begins in the large intestine), esophageal cancer (cancer that begins in the tube that connects the mouth and stomach), heart failure (HF; condition in which the heart cannot pump enough blood to other parts of the body), or heart rhythm problems such long QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause fainting or sudden death).
tell your doctor if you are breastfeeding.
Hydrocodone 10/325mg
What is Hydrocodone?
It’s very important you know what is Hydrocodone 10/325 and what it is used for. Hydrocodone acetaminophen is used to help relieve moderate to severe ongoing pain. Hydrocodone belongs to a class of drugs known as narcotic analgesics. It works in the brain to change how your body feels and responds to pain As a narcotic, hydrocodone relieves pain by binding to opioid receptors in the brain and spinal cord. It can be taken with or without food as one prefer.
Cautions when taking Hydrocodone?
Hydrocodone has a high risk for abuse and severe, possibly fatal,The risk for harm is higher if you take the wrong dose/strength, or if you take it along with other drugs that might also affect breathing or how Hydrocodone works
Possible Hydrocodone side effects
Some Hydrocodone side effects include: Nausea, vomiting, constipation, dizziness, or drowsiness may occur. Some of these Hydrocodone side effects may decrease after you have been using this medication for a while.
Norco®
(hydrocodone acetaminophen and bitartrate) 10mg/325 mg, Tablets for Oral Administration
DESCRIPTION
NORCO® (Hydrocodone bitartrate and acetaminophen) is supplied in tablet form for oral administration.
Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5).
INDICATIONS
NORCO® is indicated for the relief of moderate to moderately severe pain.
DOSAGE AND ADMINISTRATION
Dosage should be adjusted according to the severity of the pain and the response of the patient. However, it should be kept in mind that tolerance to hydrocodone can develop with continued use and that the incidence of untoward effects is dose related.
The usual adult dosage is one tablet every four to six hours as needed for pain. The total daily dosage should not exceed 6 tablets.
Renal Dose Adjustments
-Extended-release capsules: Initial dose should be lowered; monitor closely for respiratory depression and sedation
-Extended-release tablets: Lower the initial dose to one-half the normal starting dose; monitor closely for respiratory depression and sedation
Liver Dose Adjustments
Extended-release capsules:
-Mild to moderate hepatic impairment: No dose adjustment recommended
-Severe hepatic impairment: 10 mg orally every 12 hours; monitor closely for respiratory depression and sedation
Extended-release tablets: Lower the initial dose to one-half the normal starting dose; monitor closely for respiratory depression and sedation
Dose Adjustments
Abrupt discontinuation should be avoided in the physically dependent patient:
-Extended-release capsules: Titrate the dose down every 2 to 4 days; a more gradual titration may be needed in patients showing signs and symptoms of opioid withdrawal
-Extended-release tablets: Titrate the dose down every 2 to 4 days; the titrated dose should be at least 50% of the prior dose; after reaching 20 mg once a day for 2 to 4 days, the extended-release tablets can be discontinued.
Concomitant Use with CNS depressants: Lower the recommended starting dose by 20% to 30% and consider a lower dose of the concomitant CNS depressant.
CYP450 3A4 Inducers and Inhibitors: Dose adjustments may be necessary; closely monitor patients currently taking, or discontinuing CYP450 3A4 inducers and inhibitors
Increased Risk of Respiratory Depression: Consider lower initial doses, slower titrations, or alternative analgesics.
QTc Interval Prolongation: Reduce dose by 33% to 50%; consider alternative analgesics
HOW SUPPLIED
NORCO 10/325 is available as capsule-shaped, yellow tablets bisected on one side and debossed with “NORCO 539” on the other side. Each tablet contains 10 mg hydrocodone bitartrate and 325 mg acetaminophen. They are supplied as follows:
Store at 20°-25°C (68°-77°F).
Dispense in a tight, light-resistant container with a child resistant closure.
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from codeine, one of the opioid alkaloids found in the opium poppy. This medication is used to relieve a dry cough usually caused by the common
cold or other conditions as prescribed by your doctor. Relieving a cough helps you get more rest and sleep. This product contains
2 medications, hydrocodone and homatropine. Hydrocodone is a narcotic cough suppressant (antitussive) that works on certain centers in the brain to stop the urge to cough. Homatropine belongs to a class of drugs known as anticholinergics.
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This medication is generally used for short-term treatment. It should not be used for persistent coughs from smoking or long-term breathing
problems (e.g., asthma, emphysema), or for coughs with a lot of mucus or fluids (productive coughs. Cough-and-cold products have not been shown
to be safe or effective in children younger than 6 years. This product is not recommended for use in children younger than 6 years due to an increased risk of serious side effects (such as slow/shallow breathing). Some products (including some long-acting tablets/capsules) are not recommended for use in children younger than 12 years.
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These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Giving more than the recommended dose or using this medication along with other cough-and-cold products has resulted in serious (even fatal) side effects, including slowed/stopped breathing. Talk to the doctor or pharmacist before giving other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Do not use this product to make a child sleepy. Buy Hydrocodone Online from Goodwill Pharmacy the Best Online meds Store.
Order Hydrocodone Online (HOW TO USE)
Buy Hydrocodone Online and Read the Medication Guide provided by our pharmacist before you start taking hydrocodone/homatropine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Order Hydrocodone Online and take this medication by mouth with or without food, usually every 4 or 6 hours as needed or as directed by your
doctor. The dosage is based on your age, medical condition, and response to therapy. Follow your doctor’s directions closely. The manufacturer
recommends that adults should not take more than 6 tablets or 6 teaspoons (30 milliliters) daily. Children 6-12 years of age should not take more than
3 tablets or 3 teaspoonfuls (15 milliliters) daily.
If you are taking the syrup, measure the dose carefully using a special measuring device or spoon. Do not use a household spoon.
Order Hydrocodone Online but do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Best Place to Buy Hydrocodone Online is Goodwill Pharmacy .
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SIDE EFFECTS
Buy Hydrocodone Online from our Online Pharmacy , but also know that it has some side effects Some side effects of Hydrocodone are ; Nausea commonly occurs with the use of hydrocodone and usually goes away after the first few doses. Consult your doctor or pharmacist about ways to decrease nausea (e.g., taking with food, lying down for 1-2 hours with as little head movement as possible).
Lightheadedness, dizziness, drowsiness, vomiting, and constipation may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
To prevent constipation, eat a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in selecting a laxative (such as a stimulant type with stool softener).
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
PRECAUTIONS
Before taking this medication, you should know if you are allergic to hydrocodone; or to homatropine; or to other narcotic medications (such as codeine, hydromorphone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Boxed Warning:
Addiction, abuse, and misuse. Life-threatening respiratory depression. Accidental ingestion. Neonatal opioid withdrawal syndrome. Cytochrome P450 3A4 interaction. Hepatotoxicity. Risks from concomitant use with benzodiazepines or other CNS depressants.
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